Has anyone had success using AI SDRs for automated cold outbound prospecting?

Most practitioners report mixed results with fully automated AI SDRs, with many churning from AI SDR platforms within 6 months. The most successful approach is using AI as a research assistant rather than a replacement - tools like Clay can automate list building, enrichment, personalization research, and initial email creation, achieving 0.3-0.8% meeting rates (not the claimed 1%+). AI SDRs work best for horizontal solutions with large TAMs and high-volume, low-touch scenarios, but struggle with complex B2B sales cycles requiring genuine relationship building. The recommended hybrid approach involves AI handling research and initial personalization while humans review and refine before sending, with humans taking over once prospects reply or book meetings.